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Roger Hunter Selected Research

ajoene

1/2021The Garlic Compound Z-Ajoene, S-Thiolates COX2 and STAT3 and Dampens the Inflammatory Response in RAW264.7 Macrophages.
3/2019The garlic compound ajoene covalently binds vimentin, disrupts the vimentin network and exerts anti-metastatic activity in cancer cells.
5/2017The Cytotoxicity of the Ajoene Analogue BisPMB in WHCO1 Oesophageal Cancer Cells Is Mediated by CHOP/GADD153.
1/2016The garlic compound ajoene targets protein folding in the endoplasmic reticulum of cancer cells.
4/2012Structure-activity studies on the anti-proliferation activity of ajoene analogues in WHCO1 oesophageal cancer cells.
3/2011Anti-proliferation activity of synthetic ajoene analogues on cancer cell-lines.
1/2010Garlic-derived anticancer agents: structure and biological activity of ajoene.

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Roger Hunter Research Topics

Disease

8Neoplasms (Cancer)
03/2019 - 10/2008
4Malaria
11/2018 - 05/2011
1Inflammation (Inflammations)
01/2021
1Breast Neoplasms (Breast Cancer)
03/2019
1Coma (Comas)
11/2013
1Parasitemia
10/2011
1Scrapie
11/2010
1Prion Diseases (Transmissible Spongiform Encephalopathies)
11/2010
1Infections
07/2009
1Schistosomiasis (Bilharziasis)
07/2009

Drug/Important Bio-Agent (IBA)

7ajoeneIBA
01/2021 - 01/2010
3Antimalarials (Antimalarial Agents)IBA
10/2018 - 07/2009
21- myristoyl- 2- (12- ((5- dimethylamino- 1- naphthalenesulfonyl)amino)dodecanoyl)- sn- glycero- 3- phosphocholineIBA
03/2019 - 01/2016
2Proteins (Proteins, Gene)FDA Link
03/2019 - 01/2010
2hemozoinIBA
11/2018 - 10/2018
2Chloroquine (Aralen)FDA LinkGeneric
10/2018 - 05/2011
1PhytochemicalsIBA
03/2019
1VimentinIBA
03/2019
1quinolineIBA
10/2018
1A-Form DNA (A-DNA)IBA
05/2017
1Fluorescein (Funduscein)FDA LinkGeneric
01/2016
1barbituric acid (barbiturate)IBA
11/2013
1Verapamil (Calan)FDA LinkGeneric
05/2011
1AminoquinolinesIBA
11/2010
1QuinolinesIBA
11/2010
1CaspasesIBA
01/2010
1Pharmaceutical PreparationsIBA
07/2009
1Praziquantel (Biltricide)FDA Link
07/2009
1Quinacrine (Mepacrine)IBA
07/2009
1Quinidine (Chinidin)FDA LinkGeneric
07/2009
1Quinine (Quinson)FDA Link
07/2009
1Heme (Haem)IBA
07/2009
1SulfurIBA
10/2008
1sulfoxideIBA
10/2008

Therapy/Procedure

3Therapeutics
11/2013 - 07/2009
2Traditional Medicine (Folk Remedies)
05/2017 - 07/2016
1Decompression
11/2013
1Decompressive Craniectomy
11/2013
1Oral Administration
10/2011
1Intraperitoneal Injections
07/2009